Bald eagles and towering skylines grace the horizons here, contrasted by the lush landscapes and historic towns that line the riverbends from the deep south to the Midwest. Explore Hannibal, Missouri, the muse of Mark Twain, who brought this lovely region to life through his writings. Marvel at the architecture of the All-America City Dubuque, Iowa and the remarkable craftsmanship of artisans in Red Wing, Minnesota, named one of National Geographic’s most historic places.

The main stage aboard the American Queen with a singer dressed in a gold costume with wings that she is spreading while singing.
American Queen steamboat with its red paddlewheel cruising down the river
An arch dedicated to Mark Twain with a photo of him in the middle and the quote "the extensive view up and down the river is one of the most beautiful on the Mississippi" with the American Queen docked in the background