What symptoms would be expected from a car approaching its end of life?

There is no definitive timeframe for when a car reaches the end of its useful life. More likely than any significant mechanical signs is you will reach a point where the vehicle increasingly requires maintenance and then major repairs  in order to keep it running and roadworthy. For most people, the deciding factor will be balancing the cost of those repairs against the vehicle’s market value. That tipping point may be well beyond 200,000km. Many vehicles can travel  more than 200,000km with only regular maintenance and minor repairs, and this milestone doesn’t always mean the vehicle’s time is up.